教师基本信息:
姓名:陆艳
职称:副研究员
电子邮箱:lueyan@fudan.edu.cn
办公地点:必赢bwin线路检测网站江湾校区生命科学楼A309
个人简介:
女,副研究员,博士生导师。2006年作为直博生进入必赢bwin线路检测网站学习,2012年获必赢bwin线路检测网站遗传学博士学位,随后进入中国科学院上海生命科学研究院从事研究工作,历任助理研究员、副研究员。2020年进入必赢bwin线路检测网站,任副研究员。长期从事群体遗传学和基因组学相关研究,发表SCI论文40余篇。近年来以第一作者和通讯作者(含共同)在Nature, Molecular Biology and Evolution, National Science Review, Cell Reports, iScience, Genome Biology, Science China Life Sciences等国际权威杂志上发表多篇SCI研究性论文。入选上海市青年科技英才“扬帆计划”,主持国家自然科学基金青年项目、面上项目,任国家重点研发计划课题负责人和子课题负责人,研究成果入选F1000,中国生物信息学十大科学进展、中国生物信息学十大数据库、中国十大医学科技新闻等。任Hereditas编委、Phenomics青年编委,上海人类学学会“分子人类学”专业委员会秘书长、常务委员。
1. 病原驱动的人类适应性演化
2. 亚洲特有病原的遗传多样性及其与宿主的共进化
3. 人群泛基因组参考图谱构建及应用
4. 生物信息数据库和分析平台
授课情况:
《基因组学》、《现代微生物专题》、《人类进化遗传学》(本科生荣誉课程)、《专业英语》(生物信息)
招生专业
遗传学、生物信息学、微生物学等
本课题组招收博后、研究生、本科生,请通过邮箱联系必赢bwin。
课题组网站:https://pog.fudan.edu.cn/
代表性论文和论著
Xixian Ma#, Yan Lu#,*, Shuhua Xu*. Adaptive Evolution of Two Distinct Adaptive Haplotypes of Neanderthal Origin at the Immunoglobulin Heavy-chain Locus in East Asian and European Populations. Molecular Biology and Evolution.2024.41(7): msae147.
Yang Gao#, Xiaofei Yang#, Hao Chen#, Xinjiang Tan#, Zhaoqing Yang#, Lian Deng#, Baonan Wang, Shuang Kong,Songyang Li,Yuhang Cui, Chang Lei, Yimin Wang, Yuwen Pan, Sen Ma, Hao Sun, Xiaohan Zhao, Yingbing Shi, Ziyi Yang, Dongdong Wu, Shaoyuan Wu, Xingming Zhao, Binyin Shi, Li Jin, Zhibin Hu,Chinese Pangenome Consortium (CPC), Yan Lu*, Jiayou Chu*, Kai Ye*, Shuhua Xu*.A Pangenome Reference of 36 Chinese populations. Nature. 2023. 19(7968):112-121.
Qi Liu, Bo Xie, Yang Gao, Shuhua Xu* and Yan Lu*. A protocol for applying low-coverage whole-genome sequencing data in structural variation studies. STAR Protocols. 2023.4(3):102433.
Qi Liu, Ke Yang, Bo Xie, Yang Gao, Shuhua Xu*, Yan Lu*. Mapping Structural Variations in Haemaphysalis longicornis and Rhipicephalus microplus Reveals Vector–Pathogen Adaptation, iScience, 2023
Yuwen Pan, Jia Wen, Zhilin Ning, Yuan Yuan, Xubing Liu, Yajun Yang, Yaqun Guan, Yan Lu*, Dolikun Mamatyusupu, Shuhua Xu*. Comparative genomic and transcriptomic analyses reveal the impacts of genetic admixture in Kazaks, Uyghurs, and Huis, Molecular Biology and Evolution, 2023
Zeshan Lin#, Yan Lu#, Guoliang Yu; Huajing Teng, Bao Wang, Yajun Yang, Qinglan Li, Zhongsheng Sun, Shuhua Xu*, Wen Wang*, Peng Tian*. Genome-wide DNA methylation landscape of four Chinese populations and epigenetic variation linked to Tibetan high-altitude adaptation, SCIENCE CHINA Life Sciences, 2023
Xueling Ge#, Yan Lu#, Shuanghui Chen#, Yang Gao, Lifeng Ma, Lijun Liu, Jiaojiao Liu, Xixian Ma, Longli Kang*, Shuhua Xu*. Genetic origins and adaptive evolution of the Deng people on the Tibetan Plateau. Molecular Biology and Evolution. 2023.40(10):msad205.
Fang Luo, Wenbin Yang, Mingbo Yin, Xiaojin Mo, Yuhong Pang, Chengsong Sun, Bingkuan Zhu, Wei Zhang, Cun Yi, Zhidan Li, Jipeng Wang, Bin Xu, Zheng Feng, Yangyi Huang, Yan Lu*, Wei Hu*. A chromosome-level genome of the human blood fluke Schistosoma japonicum identifies the genomic basis of host-switching, Cell Reports, 2022, 39(1)
Yuwen Pan#, Chao Zhang#, Yan Lu#, Zhilin Ning, Dongsheng Lu, Yang Gao, Xiaohan Zhao, Yajun Yang, Yaqun Guan, Dolikun Mamatyusupu, Shuhua Xu. Genomic diversity and post-admixture adaptation in the Uyghurs, National Science Review, 2021, doi:10.1093/nsr/nwab